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Nephrotic Syndrome

Nephrotic syndrome is a collection of signs and symptoms that may indicate that your kidneys are not working right. Both children and adults can have nephrotic syndrome.

Causes of Nephrotic Syndrome

The causes of and treatments for nephrotic syndrome in children are sometimes different from the causes and treatments in adults.

Healthy kidneys filter waste and extra fluid from your blood.  Your body gets rid of the waste and extra fluid as urine.  In nephrotic syndrome, some protein, which normally stays in your blood, gets removed along with the waste.  This is a problem, because your body needs protein.

Protein acts like a sponge in your blood.  It holds fluid that your body needs inside your arteries and veins.  If there is not enough protein, the fluid can leak into other tissues in your body.  This can cause edema (swelling).  This usually happens around your eyes, face, belly, ankles and feet.

Learn More

Nephrotic Syndrome in Adults

Nephrotic Syndrome in Children

Tests for Kidney Disease

Illustration courtesy of the National Institute of Diabetes and Digestive and Kidney Diseases:

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