Barbara Murphy, M.D.
Dr. Murphy currently serves as the Irene and Arthur M. Fishberg Professor of Medicine. Her area of interest is transplant immunology, focusing on the Immunomodulatory role of MHC derived peptides; and the genomics of transplantation.
Dr. Murphy earned her M.B. B.A.O. B.Ch. from The Royal College of Surgeons in Ireland and went on to do an internship at Beaumont Hospital in Dublin. She completed a residency rotation at Beaumont Hospital followed by a fellowship in Clinical Nephrology also at Beaumont Hospital. Dr. Murphy completed her postdoctoral training with a fellowship in Nephrology at Brigham and Women’s Hospital, Harvard Medical School. As part of this she trained in transplant immunology at the Laboratory of Immunogenetics and Transplantation, Renal Division, Brigham and Women’s Hospital, Harvard Medical School. Among her many honors, Dr. Murphy was awarded the Young Investigator Award in Basic Science by the American Society of Transplantation in 2003. In 2005, Dr. Murphy was awarded the Irene and Dr. Arthur M. Fishberg Professor of Medicine at The Mount Sinai Hospital.
Dr. Murphy belongs to a number of professional societies including the American Society of Transplantation and the American Society of Nephrology. Among her many leadership roles at a national level, Dr. Murphy has served as the President of the American Society of Transplantation, the Executive Committee of the American Transplant Congress, and the Education Committee of the American Society of Nephrology. She is currently an Associate Editor for The Clinical Journal of the American Society of Nephrology and is co-chair of the Public Policy Committee for the American Society of Transplantation.
Dr. Murphy’s research has focused on two major areas. Having demonstrated that MHC class II peptides derived from non-polymorphic regions may inhibit the alloimmune response in vitro and in vivo, Dr. Murphy is currently investigating their mechanisms of action and their ability to prolong allograft survival in vivo. In addition, Dr. Murphy is also investigating the role of genomics to predict outcomes in transplantation, in particular the development of chronic rejection and the use of genomics to appropriately stratify patients based on immunological risk.