Tests for kidney disease

Learn about kidney tests that can help doctors find kidney disease early, such as blood tests, urine tests, kidney ultrasound and kidney biopsy.
Medically reviewed by
AKF's Medical Advisory Committee
Last updated
March 28, 2024

The only way to know how well your kidneys are working is to get tested. Kidney disease often has no symptoms until your kidneys are badly damaged. Testing is especially important if you have diabetes, high blood pressure or a family history of kidney disease. 

Ask your doctor about these kidney tests. Finding and treating kidney disease early can help you slow or stop damage to your kidneys.

Download our tests for kidney health printable guide

Blood test: eGFR

eGFR (estimated glomerular filtration rate) is a measure of how well your kidneys are working. Your eGFR is an estimated number based on a blood test and your age, sex, and body type.

eGFR is considered a mostly reliable test for doctors to know how well your kidneys are working. However, the eGFR may not be accurate if you are younger than 18, pregnant, very overweight or very muscular. In addition, other tests such as  an ultrasound or a kidney biopsy may be ordered to find a cause of your kidney disease.

Learn more about the eGFR test.

Urine test

A urine test is when a doctor examines a small amount of your urine (pee) to check for signs of kidney disease and other health problems. When your kidneys are damaged, they may let protein leak into your urine. This can be one of the earliest signs of kidney disease.

Urine tests help your doctor: 

  • Measure your kidney function 
  • Find out what stage of kidney disease you are in
  • Keep track of health problems that can cause kidney disease, such as diabetes
  • Check for complications (problems) from kidney disease such as anemia and metabolic acidosis 
  • Check for other problems such as a kidney infection or a urinary tract infection (UTI)

Learn more about a urine test. 

Blood test: Serum creatinine test

Creatinine is a waste product in your blood that comes from your muscles. Healthy kidneys filter creatinine out of your blood through your urine.

Your serum creatinine level is based on a blood test that measures the amount of creatinine in your blood. It tells how well your kidneys are working. When your kidneys are not working well, your serum creatinine level goes up.

Your doctor can also measure creatinine with a urine test.

Learn more about the serum creatinine test.

Blood urea nitrogen (BUN) test

Your blood urea nitrogen (BUN) level is based on a blood test that measures the amount of urea nitrogen in your blood. Urea nitrogen is a waste product that your body makes after it breaks down protein. Healthy kidneys take urea nitrogen out of your blood. When your kidneys are not working well, your BUN level goes up.

Learn more about the Blood urea nitrogen (BUN) test.

Cystatin C Test

The cystatin C test is a type of blood test to see how well your kidneys are working.  

Usually, to measure how well your kidneys are working, doctors check your eGFR (estimated glomerular filtration rate) by using a blood test for creatinine (a waste product made by your body's muscles). The eGFR is an estimated number to tell doctors what stage of kidney disease you have.  

Sometimes doctors may use the cystatin C test to check your eGFR if:  

  • Past kidney function test results have come back unclear  
  • Your creatinine levels are likely to vary for other reasons, such as older age or having a lot of muscle mass, like a body builder 

Imaging tests 

Imaging tests look for physical changes in your kidneys that may help find the cause of your kidney disease, such as:  

  • Abnormal size or shape of your kidneys 
  • Blood flow to your kidneys 
  • Signs of injury or damage to your kidneys 
  • Kidney stones, cysts (fluid-filled sacs) or tumors 
  • Size of or problems with your bladder (the organ that stores urine before it leaves your body) 

After an imaging test, a radiologist (a doctor specially trained in reading scan images) will read your images and give the results to your doctor. You and your doctor will go over the results and decide your next steps.  

Kidney ultrasound 

A kidney ultrasound (also called a renal ultrasound) is a safe and painless imaging test that uses sound waves to make pictures of your kidney: 

  1. You will lie down on an exam table. 
  2. The ultrasound tech (the person doing the ultrasound) will spread a warm gel on your belly over your kidney area.  
  3. The tech will rub a small probe against your skin. 
  4. The tech may ask you to hold your breath or roll on your side while the computer is measuring the sound waves as they bounce back from your body to create images. 

A kidney ultrasound takes about 20-30 minutes.  

Computed tomography (CT or CAT) scan of the kidneys 

A CT or CAT scan is a painless test that uses X-rays and computer technology to create detailed images of your kidneys: 

  1. If you have a scan with contrast, you will get the contrast (a substance you will drink or get through a needle in a vein that helps certain tissues show up more clearly). 
  2. You will lie down on an exam table that slides into a large, circle opening of a scan machine. 
  3. The tech will move to another room to control the scan. You will be able to talk with the tech through a speaker system. 
  4. The scanner will rotate around you, and you will hear clicking sounds. You will need to lie very still, and the tech may ask you to hold your breath. 
  5. If you got contrast in a vein, the tech will remove it after the scan.  

A CT scan takes about 30 to 60 minutes.  

Magnetic resonance imaging (MRI) of the kidneys 

An MRI uses magnets and radio waves to make 3D (3-dimensional) pictures of your kidneys: 

  1. You will lie down on an exam table that slides into a large tunnel-like tube in the scanner. 
  2. The tech will move to another room to control the scan. You will be able to talk with the tech through a speaker system. 
  3. The scanner will take many sets of images. You will hear loud noises coming from the scanner. 

An MRI takes about 30 to 60 minutes. 

Kidney biopsy

A kidney biopsy can help your doctor figure out what is causing your kidney problem, how severe your kidney problem is and the best treatment. 

Your doctor may suggest a kidney biopsy if tests show:

Your doctor may also suggest a kidney biopsy to find out if:

If you have any questions about why you need a kidney biopsy and how it could help treat your kidney problem, talk to your doctor. 

Learn more about a kidney biopsy.

Genetic Testing

Genetic testing is a type of medical test that looks at your DNA, the genetic code that is unique to every individual.  

This testing uses a blood or saliva (spit) sample to look at changes in your genes, chromosomes or proteins. Genes are the information inside your cells that instruct it to do certain tasks, chromosomes are structures within your body's cells that contain your genes, and proteins are built from the cells using instructions found in your genes. Changes, or mutations, in your genes may cause certain types of kidney disease. 

How much does it cost for a kidney test?

The costs of these tests depend on your insurance coverage. Call your insurance company and ask if they cover a test and how much you may have to pay. If your insurance will not cover a test, there may be programs to help you pay.  

Ask your doctor to speak with a social worker or financial counselor for help with insurance and paying for tests.  

Your donation directly supports the fight against kidney disease

For 21 consecutive years Charity Navigator™ has rated us a Top Nonprofit. Your donations allow us to help more people than any other kidney organization – from making 150 kidney transplants possible every month to delivering financial relief to 1 in 7 dialysis patients. We also fund clinical research, provide financial assistance for kidney patients affected by natural disasters, and support a National virtual pediatric camp and a Kidney Health Coach community program.