The symptoms of aHUS happen because too many blood clots form in your blood vessels.  These blood clots block regular blood flow to your body’s organs. When you have aHUS, the kidneys are affected the most compared to other organs.

aHUS is usually first discovered by doctors because you have acute kidney injury or other signs of kidney damage. Signs of kidney damage may be protein in your urine, or an abnormal eGFR, discovered by a blood test.

Other symptoms of aHUS can be:

  • Fatigue; feeling tired all the time
  • High blood pressure
  • Heart disease
  • Neurological problems like headaches, seizures, or irritability
  • Gastrointestinal problems