The treatment for lupus nephritis focuses on preventing more damage to your kidneys. Finding and treating lupus nephritis early can help prevent serious damage. Lupus damages your kidneys by causing your immune system to attack them. To prevent this from happening, your health care provider might want you to take a medicine called an immune suppressant. This type of medicine weakens your immune system so that it can’t harm your kidneys as much.

Your health care provider might also want you to take a medicine to lower your blood pressure. High blood pressure is the second most common cause of kidney failure (end-stage renal disease, or ESRD). Two common types of blood pressure medicine are ACE (angiotensin converting enzyme) inhibitors and ARBs (angiotensin receptor blockers).

Having too much fluid in your body can also raise your blood pressure and strain your heart. If your body is holding on to too much water and your feet and ankles are swelling, your health care provider might tell you to take a diuretic, also known as a water pill. This medicine can help your body get rid of some of the extra fluid it is holding on to.