aHUS is commonly treated with a drug called eculizumab. For now, it is the only medicine approved in the United States to treat aHUS.  Eculizumab can improve platelet and red blood cell counts. It may also reverse acute kidney injury and prevent kidney failure if it is taken soon enough. Eculizumab is given by injection at a doctor’s office.

Plasma therapies including infusions and exchanges are sometimes used to treat aHUS, but these methods do not treat the underlying disease. Plasma therapies work for treating aHUS in some people, but do not work for everyone.