It is not always possible to know what causes glomerulonephritis. Many diseases and conditions can lead to damage of the glomeruli, but someone may also have glomerulonephritis without ever having one of these diseases or conditions. Some of the problems that can lead to glomerulonephritis include:

  • High blood pressure
  • Diabetes
  • Cancer
  • Strep throat
  • Regularly taking more than the recommended dose of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, aspirin or naproxen
  • Bacterial infection of your heart
  • Viral infections, such as HIV, hepatitis B and hepatitis C
  • Immune diseases, such as lupus, Goodpasture syndrome and IgA nephropathy
  • Vasculitis (a condition that causes irritation to your blood vessels)