Renal news roundup from AKF

Tim Andrews made medical history as the first person to receive a human kidney transplant after living with a genetically modified pig kidney. He spent 271 days with the pig organ, which he named Wilma, which allowed him to avoid dialysis and improve his quality of life, despite ...

An analysis of data from the Medical Information Mart for Intensive Care IV database found that statin therapy was associated with lower 30-day mortality risk among patients with nontraumatic intracerebral hemorrhage (ICH) with acute kidney injury (AKI). The study in Scientific R...

A placebo-controlled study published in the New England Journal of Medicine associated pegcetacoplan with a 68.1% relative reduction in proteinuria for patients with recurrent C3 glomerulopathy or primary immune-complex membranoproliferative glomerulonephritis. Data showed 60% of...

Variant Bio (VB), based in Seattle, has spent seven years developing Inference, an artificial intelligence (AI)-based genomics platform for drug development, and now is licensing it to Boehringer Ingelheim for cardiorenal and kidney disease pharmaceutical targets. The platform us...

Serum creatinine trajectories may be important predictors of 28-day mortality in patients with acute kidney injury (AKI) on chronic kidney disease (CKD), according to a study in the European Journal of Medical Research. Five distinct patterns were identified, with moderate stable...

A study in BMC Nephrology found that starting hemodialysis with an incremental approach may help preserve remaining kidney function in patients with stage 5 chronic kidney disease. The retrospective study of 80 patients found 45% of those who began with less intensive dialysis re...

Patients with depression had a faster progression of CKD, compared with those who did not have depression, researchers reported in Frontiers in Nephrology. The risk of developing depression was higher for patients with stage 4 disease, compared with those in stage 3 or lower. HCP...

An updated clinical practice guideline from the Department of Veterans Affairs and the Department of Defense focuses on early-stage CKD management and newer pharmacologic options. The guideline, published in the Annals of Internal Medicine, includes 23 recommendations, about half...

Patients on hemodialysis were significantly less physically active on dialysis days than on interdialytic days, with morning dialysis sessions linked to greater reductions in activity. Researchers reported in the Clinical Journal of the American Society of Nephrology that the fin...