APOL1-Mediated Kidney Disease Guide
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Every person has the APOL1 (apolipoprotein L1) gene. However, mutations of the gene can raise the chance of kidney disease in people of Western and Central African descent, which may include people who identify as African American, Afro-Caribbean or Latina or Latino. Doctors may refer to this as APOL1-mediated kidney disease (AMKD). It is estimated that one in five people with two copies of APOL1 mutations get kidney disease. Learn more about AMKD with our guide.