Thrombotic thrombocytopenic purpura (TTP)
- Medically reviewed by
- AKF's Medical Advisory Committee
- Last updated
- November 1, 2021
Thrombotic thrombocytopenic purpura (TTP) is a rare blood disease, also known as microangiopathic hemolytic anemia or Moschowitz disease. TTP happens when too many blood clots have formed in your blood vessels, making it hard for oxygen to reach organs in your body like the kidneys. This can lead to kidney damage and kidney failure.
The main symptom of TTP is bruising all over the skin that looks like small purple dots. TTP can also lead to anemia. TTP is caused by gene mutations. Gene mutations are usually passed down from a parent, but can also develop during your life. The cause for the mutations is not always known. Although there is no cure or any way to prevent TTP from happening, treatments such as plasma therapies are available to keep it under control.
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