Renal news roundup from AKF

A report in the New England Journal of Medicine found that chimeric antigen receptor (CAR) T-cell therapy successfully enabled patients with highly sensitized immune systems to undergo kidney transplantation. The therapy engineers T-cells to suppress antibody-producing cells that...

A new kidney transplant risk prediction model, the mBox, has been developed to accurately assess mortality risks up to 10 years post-transplant. Published in JAMA Network Open, the study used data from 14 medical centers across the U.S. and Europe and demonstrated consistent perf...

Nephrodite has been selected to participate in the Food and Drug Administration's (FDA) Total Product Life Cycle Advisory Program (TAP) pilot with its Holly implantable continuous dialysis system, which received breakthrough device designation last year. "This recognition from th...

Both pre-existing and new-onset diabetes significantly increase mortality risk in recipients of kidney, heart, liver and lung transplants, according to a large-scale analysis presented at the Endocrine Society annual meeting. The study, which included over 730,000 transplant pati...

A study presented at the annual meeting of the European Renal Association found that dihydropyridine calcium-channel blockers, blood pressure drugs such as amlodipine and nifedipine, were associated with a 33% higher risk of kidney damage in patients with type 2 diabetes (T2D). T...

A study in Diabetes, Obesity and Metabolism finds that sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of major adverse kidney events, end-stage kidney disease (ESKD) and all-cause mortality in adults with T2D and nephrotic-range proteinuria compared with dipept...

The American College of Cardiology (ACC) and the American Heart Association (AHA) have issued a guideline to address cardiovascular-kidney-metabolic (CKM) syndrome, emphasizing integrated care across the three areas. "If we can address things earlier and also address the interrel...

The FDA has updated the label for the over-the-counter weight-loss drug orlistat to include a warning about the risk of kidney stones and kidney injury. Consumers who have a history of kidney disease or kidney stones are advised to consult a healthcare professional before taking ...

Ivan Gonzalez donated a kidney to his father, Luis Fernando Gonzalez, in 2022 after seeing his father's health decline due to kidney disease. Ivan described his decision as immediate and driven by gratitude for his father's sacrifices, emphasizing that living kidney donation is a...