Renal news roundup from AKF

Roche's sefaxersen has shown positive results in a Phase 3 trial for treating immunoglobulin A nephropathy (IgAN), a rare autoimmune kidney disease. The drug significantly reduced protein levels in urine, indicating potential improvement in kidney function. Sefaxersen, originally...

The Food and Drug Administration (FDA) has approved obinutuzumab, known by the brand name Gazyva, to treat idiopathic nephrotic syndrome in adult and pediatric patients age 2 and older. The approval is based on positive data from the Phase 3 INSHORE study, which showed that Gazyv...

CSL is paying $355 million upfront and up to $1.2 billion in milestone payments to co-develop Alentis Therapeutics' lixudebart, an anti-Claudin-1 drug in Phase 2 trials for kidney and liver diseases. CSL will fund the completion of the Phase 2 trial and a Phase 3 trial for antine...

Among patients aged 80 and older with end-stage kidney disease (ESKD), transitioning from peritoneal dialysis (PD) to hemodialysis was linked to a higher mortality risk, according to a study published in Clinical Kidney Journal. Specifically, octogenarians who made this switch sh...

Recent years have seen a marked increase in kidney-related emergency department visits during extreme heat, with studies showing up to 30% of such visits in 2025 were attributable to high temperatures. Both acute kidney injury (AKI) and the progression to chronic kidney disease (...

A study presented at a meeting of the European Association for the Study of Diabetes found people with type 2 diabetes had a 33% higher risk of death, heart failure or kidney disease within five years of diagnosis, and that risk increases to 55% over 10 years. "Our findings clear...

Pediatric hospitalizations for AKI have surged tenfold over the past 25 years, according to a study in JAMA Network Open. The study, which analyzed data from 24.3 million discharges, found that hospitalizations involving AKI increased from 15.7 per 10,000 discharges in 1997 to 16...

Tele-nephrology is emerging as a vital solution for patients with CKD, particularly in rural areas and medical deserts where access to nephrologists is limited. Phuc Nguyen, a nephrologist at Access TeleCare, highlights how tele-nephrology allows patients to receive timely care l...

Adan Garcia, a Fresno, California resident, donated a kidney to his father, who suffered from kidney failure due to Type 2 diabetes. During his recovery, Garcia began documenting his journey on social media, creating a community that has garnered over 2 million views. Garcia uses...