Renal news roundup from AKF

The Food and Drug Administration (FDA) has approved Vera Therapeutics' Trutakna for the treatment of immunoglobulin A (IgA) nephropathy, a chronic autoimmune kidney disease that can lead to organ failure. "We're extremely excited to bring Trutakna to patients," says Vera CEO Mars...

AstraZeneca and CSPC Pharmaceutical are collaborating to develop two small nucleic acid drug candidates for kidney disease using CSPC's siRNA platform and AI molecular design model. AstraZeneca will pay $30 million upfront and up to $1.7 billion in milestones and sales-based paym...

Continuous glucose monitoring (CGM) is associated with a reduced risk of all-cause mortality in patients with diabetes who are on dialysis, according to a study published in Diabetes Care. The study, which analyzed data from the Veterans Affairs healthcare system, found that CGM ...

The prevalence of chronic kidney disease (CKD) in the U.S. has remained steady at around 14.8% over the past decade, affecting an estimated 36 million adults, according to National Health and Nutrition Examination Survey data published in The New England Journal of Medicine. Desp...

Suboptimal dialysis starts are linked to lower odds of transplant referral, evaluation and wait-listing, according to a study in Nature Communications Medicine. The study found that more than half of patients had minimally optimal or nonoptimal dialysis starts, significantly redu...

Early rhythm control significantly reduces the composite risk of cardiovascular (CV) death, stroke, acute coronary syndrome and heart failure hospitalization, as compared to usual care with rate-control drugs, in people with recent atrial fibrillation (AFib) and mild to moderate ...

Serial amnioinfusions before the third trimester of pregnancy effectively mitigated the fatal effects of pulmonary hypoplasia in fetuses with kidney failure, according to a study published in JAMA. Among 32 pregnancies that chose the intervention, 29 resulted in live births and t...

The Long-term Enhanced Accountable Care Organization Design (LEAD) model is not a replacement for the Kidney Care Choices (KCC) model but it provides valuable insights into the future of value-based kidney care, write Dr. Julie Dominguez and Dr. Carney Taylor of Interwell Health....

Alieja Ardoin, a Louisiana middle school student, marked the first anniversary of his kidney transplant as he turned 13 this July. After years of managing declining kidney function due to CKD and Prune Belly Syndrome, he was placed on nightly peritoneal dialysis before receiving ...