Renal news roundup from AKF

A case report in the New England Journal of Medicine suggests that teclistamab, an immunotherapy developed for multiple myeloma, may help overcome a major barrier to kidney transplantation by reducing human leukocyte antigen (HLA) antibodies in highly sensitized patients. By targ...

Vera Therapeutics' Trutakna(atacicept-vymj) has received Food and Drug Administration (FDA) approval, offering promising stabilization of kidney function in immunoglobulin A (IgA) nephropathy patients. The approval was granted based on proteinuria data, though estimated glomeru...

By age 23, nearly 80% of young adults possess risk factors for cardiovascular-kidney-metabolic (CKM) syndrome, such as excess adiposity and metabolic abnormalities, according to a study published in Circulation: Population Health and Outcomes. Only about 20% maintained healthy we...

Children with type 1 diabetes (T1D) who experience acute kidney injury (AKI) during diabetic ketoacidosis have a fivefold increased risk of developing diabetic kidney disease (DKD) within eight years, according to a study published in AndesPediatrica. The retrospective case-contr...

Young adults with cardiovascular-kidney-metabolic syndrome show signs of early carotid artery injury, according to a study in Circulation: Population Health and Outcomes. The study shows that young adults with CKM syndrome had more cardiovascular risk factors, as measured by the ...

Patients with IgA nephropathy experience significant delays between symptom onset and diagnosis, according to a study by Dr. James Tumlin of Emory University. Patients waited an average of nine months before seeking care, mostly from primary care physicians, and referral to a nep...

A study in JAMA Network Open evaluated the effectiveness of early nephrology consultations prompted by a machine learning tool, ESTOP-AKI, in preventing AKI in high-risk patients. The trial involved 180 patients and found that early consultations did not prevent increases in seru...

Among patients with type 2 diabetes (T2D) not using insulin or thiazolidinediones, those with higher total ketone body levels within a mild hyperketonemic range had a significantly lower risk of adverse kidney events, according to a study published in Diabetes Research and Clinic...

The removal of a health equity provision from the Increasing Organ Transplant Access Model could affect more than 5,000 patients in Illinois and Indiana. The provision had addressed a race-based kidney function formula and had improved access for Black patients, but it was elimin...