Renal news roundup from AKF

Immunoglobulin A (IgA) nephropathy management is shifting from a "watch and wait" approach to a more aggressive, multitargeted strategy, driven by new insights into the disease's pathogenesis and a higher-than-expected rate of kidney failure. Recent guidelines and Food and Drug A...

R1 Therapeutics has raised $77.5 million in Series A funding to advance its therapy for chronic kidney disease (CKD) patients on dialysis with high phosphate levels. The funding will support the development of AP306, a pan-phosphate transporter inhibitor licensed from Alebund Pha...

Patients scheduled for shockwave lithotripsy to break up kidney stones said that a virtual reality (VR) briefing made them feel less anxious and better informed, researchers reported at the European Association of Urology's annual meeting. The immersive VR experience allowed user...

Researchers are developing advanced methods to detect acute kidney injury (AKI) earlier to prevent irreversible damage. Efforts include using electronic health data to flag risky medications and identifying biomarkers such as TNF-alpha and CXCL9 for more precise urine tests. Thes...

Exergaming, which combines exercise and video gaming, may increase physical activity and motivation among children and adolescents undergoing in-center hemodialysis, according to a study in Pediatric Nephrology. The ICAROS Seated Trainer allows patients to engage in digital games...

Patients with end-stage renal disease (ESRD) who have a primary care physician (PCP) relationship may experience fewer emergency department (ED) visits than those who don't have a PCP, according to a study in JAMA Network Open. The study, which analyzed data from 181,520 Medicare...

Researchers reported in the journal Pediatric Nephrology that 23.4% of children with juvenile idiopathic arthritis (JIA) developed AKI at disease onset, with a mean age of 6.7 years at diagnosis. Independent predictors of AKI included younger age, high C-reactive protein levels a...

Moderna's mRNA-1345 vaccine was found to be safe and immunogenic for recipients of solid organ transplants, according to a study in the journal Clinical Infectious Diseases. The vaccine induced strong neutralizing antibody responses against RSV-A and RSV-B after one dose, with ad...

Routine testing for Kaposi sarcoma-associated herpesvirus (KSHV) in organ donors and recipients is not standard practice, raising concerns about undetected infections. Cases of KSHV infections among transplant recipients has increased in the last five years, underscoring the need...