
Blog post
Your family tree holds clues to your kidney health – here's how

When you think about what runs in your family, you might picture things like your grandfather's good looks or your uncle's sense of humor. But did you know that your family health history, especially your DNA and genes, can play a big role in kidney health?
Don't worry if those words sound like science class all over again. Let's walk through it together like you would with a family member.
What are DNA and genes?
DNA, or deoxyribonucleic acid, is like a recipe book that lives inside almost every cell in your body. For example, if your mom has dimples and your dad has dimples...you might get dimples too! The "recipes" in this book are called genes, and they help decide how your body works, including how your kidneys filter waste and control blood pressure.
Sometimes, those recipes of the DNA include little edits or a small change in the instructions — what doctors call "genetic changes" or "mutations." Some of these changes can increase your chances of developing kidney disease or make the condition harder to manage. And because families often share genes, these changes can be passed down from one generation to the next.
Why family health history matters
Talking to your family about kidney disease and other health issues isn't always easy — but it matters. If someone in your family is living with kidney failure or has needed dialysis or a kidney transplant, that could mean you or other relatives might face a higher risk of kidney failure too. Sharing this information with a health care professional can help them catch problems early and work with you on ways to prevent or delay progression of kidney disease.
Here's the good news: Knowing your risks gives you power. It means you can take action earlier. This might mean getting your blood pressure checked more often, following a kidney-friendly eating plan — which you can find more information about on the American Kidney Fund (AKF)'s Kidney Kitchen® — or just being more aware of how your body feels day to day.
Helpful reminders
- Genetic risk isn't a guarantee that you will develop kidney disease. It just means you may need to be a little more watchful.
- Early detection is key. Ask your doctor about getting blood and urine (pee) tests for kidney disease.
- You're not alone. Many people are living full lives with kidney disease thanks to better information, treatments and support.
It's never too early to start these conversations — whether you're a teenager or an adult. The more you know about your family's health, the better prepared you are to keep your kidneys strong and your future bright.
For more information about family health history, including ways to start a conversation about health history and a sample family health history chart, explore AKF's Genes to Generation tool.